Medical Encyclopedia

Neuropathy, or nerve disease, is known to be the dominant ailment and one of the most painful complications of diabetes. The most typical symptoms which are attributed to neuropathy are damage to the nerve of the limbs, numbness and a loss of sensation in the limbs, painful sensations in the limbs which are not responsive to traditional pain-relievers.

With diabetes your susceptibility to a wide range of diseases threatening your whole-body function and well-being increases greatly. The eyes are particularly liable to damage inflicted on small blood vessels of the retina, i.e. the condition known as retinopathy.

Benfotiamine is effective as a nutrient for people trying to ward off the adverse effects of sustained high blood sugar levels. Chronic exposure to high blood glucose levels inevitably leads to cellular dysfunction and results in glucose toxicity and further in chronic oxidative stress. Glucose toxicity is a condition of high glucose concentration. It hampers the mechanisms counteracting the process by which high blood sugar level alters cell and tissue structure thus creating conditions favorable to the development of diabetes-related complications which in the long run can be fatal. In general, thiamine is necessary for the proper regulation of glucose metabolism in diabetes sufferers. Benforiamine as a synthetic derivative of thiamine (vitamin B1) addresses the effects of high blood glucose and normalizes glucose metabolism.

Diabetes is an insidious disease which is fraught with a number of serious complications which can be fatal if no control of blood glucose level is exercised. A regular control of blood sugar is an indispensable condition of a patient's well-being. To this effect vitamins of B-group have proved to be effective as thiamine supplements can reverse many of early diabetes-related complications.

Benfotiamine is a man-made form of thiamine (vitamin B1) which can produce beneficial effects on a patient's overall health condition. It is said to be the most effective medicine of this type because of its ability to reduce the level of advanced glycation end products in the body. Benfotiamine also lowers the amount of sugar in a patient's blood by decreasing sugar production and by burning sugar in the body. And as its effect is mostly therapeutical, benfotiamine may be used as a treatment for both types of diabetes thus helping insulin-dependent and insulin-independent patients.

Diabetic nephropathy is one of the most dreaded complications of diabetes as it leads to the progression of the end-stage renal disease. When kidney operation deteriorates, the kidneys fail to perform their primary filtrating function. The outcome is far from promising: patients have to resort to kidney dialysis which gives them from 4 to 7 years and then, if possible, to transplantation with a risk of cardiovascular morbidity and mortality.